DaGO-Fun: tool for Gene Ontology-based functional analysis using term information content measures

BMC Bioinformatics

Table 4 IC-based GO semantic similarity tools and functional similarity measures (FSM) they support

		GO-semantic similarity features implemented
Tool	Format	Family	Approach	FSM
G-SESAME	Web	Topology-based	Wang et al.	ABM
		Annotation-based	Classical Resnik, Lin	Average
			and Jiang & Conrath
ProteInOn	Web	Annotation-based	Classical Resnik, Lin	BMA and
			and Jiang & Conrath	SimGIC
			GraSM
FuSSiMeg	Web	Annotation-based	Classical Resnik, Lin	Max
			and Jiang & Conrath
			GraSM
FunSimMat	Web	Annotation-based	Classical Resnik, Lin	ABM
			and Jiang & Conrath
			SimRel (enhancement)
SemSim	R	Topology-based	Wang et al. Method	ABM
		Annotation-based	Classical Resnik, Lin	Average
			and Jiang & Conrath
			SimRel (enhancement)
csbl.go	R	Annotation-based	Classical Resnik, Lin	SimGIC
			and Jiang & Conrath	Average
			GraSM and SimRel

ISSN: 1471-2105