Skip to main content
Figure 6 | BMC Bioinformatics

Figure 6

From: Calculation of Tajima’s D and other neutrality test statistics from low depth next-generation sequencing data

Figure 6

Difference between the full ML and the EB method under a selective sweep. Difference between estimated Tajima’s D and known Tajima’s D, left plot ‘a)’ is using the ML for every 50 kb region, right figure ‘b)’ is using the EB approach with a 1 Mb estimated SFS as prior for all 50 kb regions. The targeted site for selection is in the middle and we see that the local 50 kb ML has some very positive outliers in this region. This is contrasted by the EB method where we have some negative outliers. However we can see that the median for the EB method in the middle region is shifted to a positive value, whereas the median for the 50 kb ML is overall relatively close to zero. Also notice the difference of scaling in the y-axis.

Back to article page