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Table 1 ScreenSifter in comparison to related tools

From: ScreenSifter: analysis and visualization of RNAi screening data

 

Input file

Metadata

Data-base

QC/ Normalization

Hits Identification

On target analysis

Gene Ontology

Protein-protein interaction

Programming language

Required programming knowledge

GUI

Operating system

Output results

cellHTS [5]

Text file

Description files need to be loaded along with data file

No

Yes

Yes

No

Yes

No

R package

Yes

No

Windows, Linux, Mac (R command)

HTML output,

RNAither [6]

Text file

 

No

Yes

Yes

No

Yes

No

R package

Yes

No

Windows, Linux, Mac (R command)

HTML output

Screensaver [7]

Excel workbooks

Yes

Yes

No

No

No

No

No

Java

No

Yes

Cross-platform

Excel workbooks, SD files

HTSanalyzeR [8]

Pre-processed data from cellHTS2

No

No

No

No

No

Yes

Yes

R package

 

No

Windows, Linux, Mac (R command)

Figures,

HTML tables

ScreenSifter

CSV file

Customized Project, Screen and Table data description through GUI

Yes

Yes

Yes

Yes

Yes

Yes

Python, wxPython

No

Yes

GUI: Windows, Mac

Tab-delimited text file, visualization plots

            

Source code: Linux