Table 2 Comparison of different methods for classifying exposed/buried residues on the independent test set without interface TM residues
From: Lipid exposure prediction enhances the inference of rotational angles of transmembrane helices
Measurements | TMexpo | MPRAP | TMX | Rhythm (membrane-coil) | Rhythm (channel) |
|---|---|---|---|---|---|
MCC | 0.51 | 0.35 | 0.44 | 0.32 | 0.29 |
Sensitivity | 81.30% | 64.24% | 75.60% | 73.53% | 67.25% |
Specificity | 69.15% | 70.31% | 67.99% | 58.03% | 61.80% |
Precision | 72.73% | 68.48% | 68.69% | 65.02% | 65.17% |
Accuracy | 75.26% | 67.27% | 71.66% | 66.01% | 64.61% |