Table 4 Comparison of different methods for classifying exposed/buried residues on 3,553 entire TM residues of the independent test set by rASA derived from both subunit structure and complete structure (in parentheses)
From: Lipid exposure prediction enhances the inference of rotational angles of transmembrane helices
Measurements | TMexpo | MPRAP | TMX | Rhythm (membrane-coil) | Rhythm (channel) |
|---|---|---|---|---|---|
MCC | 0.49 (0.48) | 0.33 (0.34) | 0.41 (0.41) | 0.30 (0.27) | 0.29 (0.29) |
Sensitivity | 79.79% (81.29%) | 62.85% (64.55%) | 73.70% (73.70%) | 72.43% (72.36%) | 67.07% (68.18%) |
Specificity | 68.70% (65.69%) | 70.19% (68.93%) | 67.71% (67.71%) | 57.64% (54.64%) | 61.86% (60.42%) |
Precision | 75.56% (70.45%) | 71.53% (67.40%) | 72.18% (72.18%) | 68.43% (62.57%) | 68.45% (64.06%) |
Accuracy | 74.78% (73.51%) | 66.20% (66.74%) | 70.90% (70.90%) | 65.91% (63.71%) | 64.74% (64.37%) |