Figure 3

Identifying constitutive exons. Plot of exons selected by exClust for a particular gene. A clustering dedrogram of the exons is formed by apply Ward’s linkage hierarchical clustering to the distance matrix $1-{\Sigma }_g^E$. Cutting the dendrogram at the dashed red line results in the creation of three subgroups of exons (each box here contains a subgroup). For each subgroup the average coverage of the two exons in that subgroup with the highest coverage is calculated. The subgroup with the highest average coverage (the shaded subgroup) is selected to represent the DSC exons for this gene.