Table 1 Annotation concept values and their definitions
From: CoMAGC: a corpus with multi-faceted annotations of gene-cancer relations
Concept | Value | Definition |
|---|---|---|
CGE | increased | Expression level of the gene is increased. |
decreased | Expression level of the gene is decreased. | |
CCS | normal- >normal | The cell or tissue remains as normal after the change in the gene’s expression level. |
normal- >cancer | The cell or tissue acquires cancerous properties as the gene expression level changes; some cancerous properties of the cell or tissue are strengthened as the gene expression level changes. | |
cancer- >cancer | There’s no change in the cancerous properties of the cell or tissue despite the change in the expression level of the gene. | |
cancer- >normal | The cell or tissue loses some cancerous properties as the gene expression level changes; some cancerous properties of the cell or tissue are weakened as the gene expression level changes. | |
unidentifiable | The information about whether or not the gene expression level change accompanies cell or tissue state change is not provided. | |
IGE | up-regulated | The initial gene expression level is higher than the expression level of the gene in the normal state. |
down-regulated | The initial gene expression level is lower than the expression level of the gene in the normal state. | |
unchanged | The initial gene expression level is comparable to the expression level of the gene in the normal state. | |
unidentifiable | The information about the initial gene expression level is not provided. | |
PT | observation | Cell or tissue change accompanied by the gene expression level change is reported as observed but the causality between the two is not claimed. |
causality | The causality between the gene expression level change and the cell or tissue change is claimed. |