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Table 8 Oncogenes and tumor suppressor genes in CoMAGC

From: CoMAGC: a corpus with multi-faceted annotations of gene-cancer relations

Cancer types Oncogenes Tumor suppressor genes
Prostate cancer FGF6u, PRKAR1Ac, SPP1c, ARv, PTGS2c, CCND1vc, AKT1uvc, MMP2c, BCL2uvc EAF2c, TFAP2Atc, WWOXutc, BRCA2utvc, PRKCDu, NKX3-1utc, MAPK8c, MAPKAPK5ut, NGFRt, ESR1c, CDKN1Bc, NDRG1tc, BTG2tc, RBP1c, NFKBIAc, TGFB1tc
Breast cancer TGFB1c, VEGFAc, ERBB2uvc, CCND1uvc, AGR2u, JUNuc, FOSuc, C11orf30c, AKTuc, PAK1c, FASNc, SRCuc RBP1c, PFN1tc, PTENutvc, IGFBP3tc, CDKN1Atc, ESR1c, TGFB1tc, MAPK14c
Ovarian cancer PLAUc, TOP1u, VEGFAc, PAK1c, HGFc, MYCuvc, AKT2uc, ERBB2uvc BRCA1utvc, BCL2vc, CAV1tc, CADM1utc, DUSP6tc
  1. Genes marked with superscripts u, c, t and v are validated with UniprotKB [31], Cancer Genes database [35], TSGene [33] and the cancer gene list by Vogelstein and colleagues [34], respectively.