Cheminformatic models based on machine learning for pyruvate kinase inhibitors of Leishmania mexicana

BMC Bioinformatics

Table 2 Significantly enriched substructures in the active dataset

Serial no.	Actives	Inactives	Chi-square	p-value	Enrichment factor
Scaffold 1	12	3	2553.48	0.00E + 00	1065.89
Scaffold 2	13	29	1054.51	0.00E + 0	119.45
Scaffold 3	11	82	327.68	3.08E-73	35.74
Scaffold 4	12	143	226.03	4.36E-51	22.36
Scaffold 5	19	234	346.19	2.86E-77	21.36
Scaffold 6	18	223	325.98	7.22E-73	21.50
Scaffold 7	12	271	113.69	1.52E-26	11.79

ISSN: 1471-2105