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Table 1 Evaluation of analysis methods

From: A novel phenotypic dissimilarity method for image-based high-throughput screens

Method

Replicate

  Z’ factor

 

GO enrichment

 

correlation

siUBC

siCLSPN

 

PCA

0.74

-0.74

-1.31

88

Factor analysis

0.39

-1.87

-0.12

92

KS statistic

0.66

0.07

0.21

51

SVM weight vector

0.07

-84.94

-3.49

101

SVM supervised

0.75

-0.29

-1.34

83

PhenoDissim*

0.75±0.001

0.56±0.01

0.40±0.01

131±18

  1. * mean ± standard deviation for three independent runs.