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Table 5 Tissue specific transporters

From: An integrated pharmacokinetics ontology and corpus for text mining

Gene Aliases Tissue type Function
ABCB1 P-gp, MDR1 Intestinal enterocyte, kidney proximal tubule, hepatocyte (canalicular), brain endothelia Efflux
ABCG2 BCRP Intestinal enterocyte, hepatocyte (canalicular), kidney proximal tubule, brain endothelia, placenta, stem cells, mammary gland (lactating) Efflux
SLCO1B1 OATP1B1, OATP-C, OATP2, LST-1 Hepatocyte (sinusoidal) Uptake
SLCO1B3 OATP1B3, OATP-8 Hepatocyte (sinusoidal) Uptake
SLC22A2 OCT2 Kidney proximal tubule Uptake
SLC22A6 OAT1 Kidney proximal tubule, placenta Uptake
SLC22A8 OAT3 Kidney proximal tubule, choroid plexus, brain endothelia Uptake