From: An integrated pharmacokinetics ontology and corpus for text mining
Gene | Aliases | Tissue type | Function |
---|---|---|---|
ABCB1 | P-gp, MDR1 | Intestinal enterocyte, kidney proximal tubule, hepatocyte (canalicular), brain endothelia | Efflux |
ABCG2 | BCRP | Intestinal enterocyte, hepatocyte (canalicular), kidney proximal tubule, brain endothelia, placenta, stem cells, mammary gland (lactating) | Efflux |
SLCO1B1 | OATP1B1, OATP-C, OATP2, LST-1 | Hepatocyte (sinusoidal) | Uptake |
SLCO1B3 | OATP1B3, OATP-8 | Hepatocyte (sinusoidal) | Uptake |
SLC22A2 | OCT2 | Kidney proximal tubule | Uptake |
SLC22A6 | OAT1 | Kidney proximal tubule, placenta | Uptake |
SLC22A8 | OAT3 | Kidney proximal tubule, choroid plexus, brain endothelia | Uptake |