Figure 2From: The causal effect of red blood cell folate on genome-wide methylation in cord blood: a Mendelian randomization approachPyrosequencing the regions surrounding four of the most significant loci suggest site-specific changes reflect regional methylation variation associated with RBC folate; change in methylation level (%) per one unit increase log RBC folate estimated using MR among the loci assayed by pyrosequencing (blue) and on the microarray (red). Regional changes were visualized by a loess curve of the site-specific estimates plotted against genomic location.Back to article page