|
Symbol
|
Chr
|
UCSC annotated features
|
CpG island
|
Δ β-value
|
Bootstrap 95% CI
|
|---|
|
OBFC2B
|
12
|
Promoter associated
|
Shore
|
0.386
|
(0.227, 0.551)
|
|
GPR75; LOC100302652
|
2
|
5′UTR; 1st Exon; Enhancer
|
Island
|
0.349
|
(0.184, 0.515)
|
|
AIRE
|
21
|
Within 100 bp of TSS
|
Island
|
0.267
|
(0.094, 0.444)
|
|
MIMT1; PEG3;ZIM2
|
19
|
Within 500 bp of TSS; 5′UTR; 5′UTR
|
Island
|
0.207
|
(0.088, 0.332)
|
|
CIRBP; C19orf24
|
19
|
Body; Within 1000 bp of TSS
|
Island
|
0.176
|
(0.097, 0.256)
|
|
SMG6; SRR
|
17
|
Within 500 bp of TSS; 5′UTR
|
Shore
|
0.125
|
(0.039, 0.214)
|
|
GPR12
|
13
|
5′UTR
|
Island
|
-0.095
|
(-0.161, -0.030)
|
- For each significant locus, including RefSeq symbol for gene(s) in closest proximity, chromosome, UCSC annotated feature, relation to UCSC CpG island. Effect estimates were reported for sites for which from the two-stage least squares (TSLS) modeling the square-root arcsine beta-values were significant at the 0.05 α-level, adjusting for whether conception was planned. Without this variance stabilizing transformation, the effect estimates are unbiased, but inference will not be correct. For interpretability, effect estimates were calculated among the significant sites without the transformation and 95% confidence interval for 1000 bootstrapped replicates were reported.
