Normalization of quantified colony measurements. A. Scanned image of one of three replicates used in B-E. The shading of each cell represents the corrected colony size as indicated by the color key and each heatmap shows the mean of three biological replicates. B. Heatmap of uncorrected colony sizes. C. Heatmap after applying row/column correction. D. As C, but with spatial correction also applied. E. As D, but with competition correction also applied.