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Table 1 Summary of the data used at pN/pS analysis

From: The evolutionary rate of antibacterial drug targets

Reference genome (strain with experimental data on essential genes; NCBI Taxonomy ID in brackets)

Other strains with complete pairwise alignments with reference genome (NCBI Taxonomy IDs)

The number of all genes*

The number of essential genes*

The number of drug targets*

Escherichia coli K12 ( 83333)

155864, 199310, 316407, 331111, 331112, 362663, 364106, 386585, 405955

4294

771

41

(3104)

(616)

(31)

Francisella novicida U112 (401614)

119857, 177416, 393011, 393115, 418136, 458234

1719

391

34

(1065)

(320)

(32)

Haemophilus influenzae Rd KW20 (71421)

262727, 262728, 281310, 374927, 374928, 374930, 374931, 374932, 374933, 375063, 375177, 375432

1581

477

39

(1024)

(399)

(34)

Helicobacter pylori 26695 ( 85962)

357544, 85963

1576

336

30

(992)

(292)

(28)

Pseudomonas aeruginosa UCBPP-PA14 ( 208963)

208963, 381754

5892

335

40

(4530)

(305)

(36)

Salmonella typhimurium LT2 ( 99287)

209261, 220341, 295319, 321314

4425

481

41

(3140)

(403)

(31)

Staphylococcus aureus N315 ( 93061)

158878, 158879, 196620, 273036, 282458, 282459, 359786, 359787, 367830, 418127, 426430, 93062

2892

351

35

(1918)

(277)

(28)

Streptococcus pneumoniae TIGR4 ( 170187)

171101, 373153, 406556, 406557, 406558, 406559, 406560, 406561, 406562, 406563

1965

195

37

  

(1532)

(175)

(33)

  1. *All genes, essential genes and drug targets comprised the three groups of genes compared in our study. The final analysis was restricted to genes for which no recombination events were detected, numbers of which are presented in brackets.
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BMC Bioinformatics

ISSN: 1471-2105

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