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Table 3 GO analysis for slowly evolving genes

From: The evolutionary rate of antibacterial drug targets

GO P-value Study-fraction Population-fraction Description
GO:0005198 2.7e-37 0.00523 0.0359 structural molecule activity
GO:0005515 1.8e-12 0.0257 0.0685 protein binding
GO:0005488 2.9e-12 0.274 0.373 binding
GO:0019843 1.4e-06 0.0028 0.0194 rRNA binding
GO:0015453 0.00043 0.000997 0.00627 oxidoreduction-driven active transmembrane transporter activity
GO:0000104 0.0076 0.000436 0.00285 succinate dehydrogenase activity
GO:0016667 0.011 0.00567 0.012 oxidoreductase activity, acting on a sulfur group of donors
GO:0003735 0.014 0.00392 0.0308 structural constituent of ribosome
GO:0015078 0.027 0.00361 0.00856 hydrogen ion transmembrane transporter activity
GO:0046872 0.045 0.0756 0.105 metal ion binding
  1. Enrichment of GO terms (molecular function domain): data for slowly evolving genes. Ten percent of genes (of eight studied species) with the lowest pN/pS rank comprised the study set. Genes with reliable pN/pS (of eight studied species) comprised the population set. Analysis was performed using Ontologizer (with Benjamini-Hochberg correction for multiple testing and Parent-child-Union Settings).
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BMC Bioinformatics

ISSN: 1471-2105

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