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Table 1 Estimates of the mean time of alteration in cell divisions with its 90% CI from ovarian data

From: Using passenger mutations to estimate the timing of driver mutations and identify mutator alterations

Gene or region

Mean time of alteration

90% CI

 

in cell divisions

 

1p34.2(MYCL1), Amp

307

(67,731)

3q26.2(MECOM), Amp

473

(413,688)

8p21.2(PPP2R2A), Del

6

(0,326)

8q24.21(MYC), Amp

10

(0,383)

10q23.31(PTEN), Del

545

(215,922)

11q14.1(ALG8), Amp

382

(167,830)

12p12.1(KRAS), Amp

62

(47,252)

13q14.2(RB1), Del

256

(196,602)

16q23.1(WWOX), Del

790

(101,851)

17q11.2(NF1), Del

375

(282,637)

19p13.13, Amp

445

(5,729)

19q12(CCNE1), Amp

280

(5,453)

20q13.12(ZMYND8), Amp

111

(81,359)

22q13.33, Del

0

(0,0)

BRCA1

113

(2,132)

BRCA2

2

(0,2)

CSMD3

426

(350,548)

FAT3

338

(288,745)

NF1

177

(73,684)

USH2A

521

(45,690)

  1. The mean time of alteration for each gene/region is calculated by averaging the posterior mean of the alteration time of the gene/region among samples in which it is altered.
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BMC Bioinformatics

ISSN: 1471-2105

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