Figure 1

Characterization of methods and datasets. (a) Multi-dimensional scaling (MDS) plot of all 12 methods based on the average dissimilarity matrix of six examples and (b) The box-plots of entropies in six data sets. Colors (red, green and blue) indicate clusters of methods with similar DE detection ordering. High entropies indicate that high consistency of DE gene detection across studies (e.g. MDD). Low entropies show greater heterogeneity in DE gene detection (e.g. prostate cancer).