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Table 2 Predictive performances estimated by the log-rank tests of the 11 pathways for five lung adenocarcinoma datasets

From: Identification of reproducible gene expression signatures in lung adenocarcinoma

Pathway (Gene Number) Database Shedden GSE3141a GSE8894a GSE11969a Beer Significance Resampling
Apoptotic execution phase (16) Reactome 1.16E-05 0.0038 0.0002 0.0008 0.0332 5 0.000
Biocarta cell cycle pathway (7) Biocarta 2.53E-08 0.0596 0.0012 0.025 0.1527 3 0.006
Cell cycle (46) KEGG 1.64E-04 0.0214 0.0050 0.0057 0.2008 4 0.053
Apoptosis (16) KEGG 6.50E-06 0.673 0.0191 0.0838 0.0468 3 0.059
Caspase cascade in apoptosis (9) PID 4.82E-04 0.2174 0.2737 0.3716 0.0055 2 0.077
APC C-mediated degradation of cell cycle proteins (32) Reactome 3.27E-05 0.2322 0.0120 0.0075 0.5752 3 0.159
Regulation of mitotic cell cycle (32) Reactome 3.27E-05 0.2322 0.0120 0.0075 0.5752 3 0.159
Polo-like kinase signaling events in the cell cycle (42) PID 5.86E-05 0.4168 0.0298 0.0389 0.229 3 0.192
Intrinsic pathway for apoptosis (9) Reactome 2.22E-06 0.1404 0.3642 0.9689 0.4496 1 0.198
Apoptosis (43) Reactome 7.58E-06 0.0136 0.0598 0.0112 0.3525 3 0.211
Cell cycle mitotic (60) Reactome 1.16E-05 0.2992 0.0008 0.0007 0.085 3 0.281
  1. aOnly adenocarcinoma patients were analyzed here.