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Table 2 Predictive performances estimated by the log-rank tests of the 11 pathways for five lung adenocarcinoma datasets

From: Identification of reproducible gene expression signatures in lung adenocarcinoma

Pathway (Gene Number)

Database

Shedden

GSE3141a

GSE8894a

GSE11969a

Beer

Significance

Resampling

Apoptotic execution phase (16)

Reactome

1.16E-05

0.0038

0.0002

0.0008

0.0332

5

0.000

Biocarta cell cycle pathway (7)

Biocarta

2.53E-08

0.0596

0.0012

0.025

0.1527

3

0.006

Cell cycle (46)

KEGG

1.64E-04

0.0214

0.0050

0.0057

0.2008

4

0.053

Apoptosis (16)

KEGG

6.50E-06

0.673

0.0191

0.0838

0.0468

3

0.059

Caspase cascade in apoptosis (9)

PID

4.82E-04

0.2174

0.2737

0.3716

0.0055

2

0.077

APC C-mediated degradation of cell cycle proteins (32)

Reactome

3.27E-05

0.2322

0.0120

0.0075

0.5752

3

0.159

Regulation of mitotic cell cycle (32)

Reactome

3.27E-05

0.2322

0.0120

0.0075

0.5752

3

0.159

Polo-like kinase signaling events in the cell cycle (42)

PID

5.86E-05

0.4168

0.0298

0.0389

0.229

3

0.192

Intrinsic pathway for apoptosis (9)

Reactome

2.22E-06

0.1404

0.3642

0.9689

0.4496

1

0.198

Apoptosis (43)

Reactome

7.58E-06

0.0136

0.0598

0.0112

0.3525

3

0.211

Cell cycle mitotic (60)

Reactome

1.16E-05

0.2992

0.0008

0.0007

0.085

3

0.281

  1. aOnly adenocarcinoma patients were analyzed here.