From: Identification of reproducible gene expression signatures in lung adenocarcinoma
Pathway (Gene Number) | Database | Shedden | GSE3141a | GSE8894a | GSE11969a | Beer | Significance | Resampling |
---|---|---|---|---|---|---|---|---|
Apoptotic execution phase (16) | Reactome | 1.16E-05 | 0.0038 | 0.0002 | 0.0008 | 0.0332 | 5 | 0.000 |
Biocarta cell cycle pathway (7) | Biocarta | 2.53E-08 | 0.0596 | 0.0012 | 0.025 | 0.1527 | 3 | 0.006 |
Cell cycle (46) | KEGG | 1.64E-04 | 0.0214 | 0.0050 | 0.0057 | 0.2008 | 4 | 0.053 |
Apoptosis (16) | KEGG | 6.50E-06 | 0.673 | 0.0191 | 0.0838 | 0.0468 | 3 | 0.059 |
Caspase cascade in apoptosis (9) | PID | 4.82E-04 | 0.2174 | 0.2737 | 0.3716 | 0.0055 | 2 | 0.077 |
APC C-mediated degradation of cell cycle proteins (32) | Reactome | 3.27E-05 | 0.2322 | 0.0120 | 0.0075 | 0.5752 | 3 | 0.159 |
Regulation of mitotic cell cycle (32) | Reactome | 3.27E-05 | 0.2322 | 0.0120 | 0.0075 | 0.5752 | 3 | 0.159 |
Polo-like kinase signaling events in the cell cycle (42) | PID | 5.86E-05 | 0.4168 | 0.0298 | 0.0389 | 0.229 | 3 | 0.192 |
Intrinsic pathway for apoptosis (9) | Reactome | 2.22E-06 | 0.1404 | 0.3642 | 0.9689 | 0.4496 | 1 | 0.198 |
Apoptosis (43) | Reactome | 7.58E-06 | 0.0136 | 0.0598 | 0.0112 | 0.3525 | 3 | 0.211 |
Cell cycle mitotic (60) | Reactome | 1.16E-05 | 0.2992 | 0.0008 | 0.0007 | 0.085 | 3 | 0.281 |