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Table 5 SVM-based prediction performances for four different types of prediction methods using equal positive and negative instances

From: Prediction of vitamin interacting residues in a vitamin binding protein using evolutionary information

Prediction

Binary approach

PSSM approach

 

Sensitivity

Specificity

Accuracy

MCC

Sensitivity

Specificity

Accuracy

MCC

VIRs

65.98 ± 0.85

65.85 ± 0.52

65.91 ± 0.60

0.32 ± 0.01

75.80 ± 0.35

77.07 ± 0.69

76.43 ± 0.47

0.53 ± 0.01

VAIRs

62.09 ± 2.01

61.87 ± 2.92

61.99 ± 1.30

0.24 ± 0.03

73.25 ± 2.43

73.83 ± 0.95

73.54 ± 1.47

0.47 ± 0.03

VBIRs

68.55 ± 0.75

68.37 ± 0.83

68.47 ± 0.44

0.37 ± 0.01

80.08 ± 0.61

82.49 ± 0.79

81.29 ± 0.23

0.63 ± 0.01

PLPIRs

76.74 ± 1.73

74.91 ± 1.42

75.82 ± 1.32

0.52 ± 0.03

89.85 ± 0.87

89.85 ± 1.16

89.84 ± 0.70

0.80 ± 0.01

  1. The values of standard errors are also given with performances.