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Table 2 Precision coverage function estimated after different QC procedures for duplicate- and multi-reads

From: Estimation of CpG coverage in whole methylome next-generation sequencing studies

  multi multi no multi no multi
  duplicate no duplicate duplicate no duplicate
# reads/sample 297,405 253,601 217,745 184,853
Mean −0.0078 −0.0079 −0.0112 −0.0132
Standard deviation 0.0214 0.0217 0.0222 0.0243
Absolute difference 0.0178 0.0181 0.0194 0.0207
  1. Note: # reads/sample is the number of reads around isolated CpGs used as input for our estimation method.