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Table 2 Significantly enriched scaffolds in the active dataset

From: Predictive modeling of anti-malarial molecules inhibiting apicoplast formation

Scaffold No. Structure Actives Inactives Chi-square p-value Enrichment Factor
Scaffold 1 21 4 8.52 3.51E-03 46.39
Scaffold 2 4 1 26.70 2.37E-07 35.34
Scaffold 3 25 17 23.61 1.18E-06 12.99
Scaffold 4 7 7 12.78 3.49E-04 8.83
Scaffold 5 2 2 11.75 6.07E-04 8.83
Scaffold 6 2 2 6.95 8.38E-03 8.83
Scaffold 7 95 166 196.90 9.88E-45 5.05
Scaffold 8 6 11 17.67 2.62E-05 4.82
Scaffold 9 43 80 82.84 8.89E-20 4.74
Scaffold 10 24 54 36.26 1.72E-09 3.92
Scaffold 11 4 9 6.04 1.40E-02 3.92
Scaffold 12 22 54 29.36 5.99E-08 3.60
Scaffold 13 201 570 241.30 1.58E-48 3.11
Scaffold 14 10 29 10.48 1.20E-03 3.04
Scaffold 15 134 392 135.32 2.81E-31 3.02
Scaffold 16 9 31 6.66 9.83E-03 2.56
Scaffold 17 48 181 29.25 6.36E-08 2.34
Scaffold 18 126 488 72.29 1.85E-17 2.28
Scaffold 19 41 178 17.57 2.77E-05 2.03
Scaffold 20 164 722 67.82 1.79E-16 2.00