|
Feature
|
Matthew’s correlation (%)
|
|---|
|
C
|
D
|
A
|
K
|
All residues
|
Conserved > 3.5
|
|
X
| | | |
16.28
|
22.05
|
| |
X
| | |
15.51
|
26.68
|
| | |
X
| |
10.12
|
27.56
|
|
X
| |
X
| |
18.71
|
28.16
|
| |
X
|
X
| |
19.78
|
32.48
|
|
X
|
X
| | |
20.56
|
27.67
|
|
X
|
X
|
X
| |
20.68
|
28.95
|
| | |
X
|
X
|
10.95
|
25.48
|
- C, sequence conservation; D, distance to the GCM; A, residue type; K, closeness. A check symbol on a column indicates that the feature was included in training. The Matthew’s correlation coefficient, expressed as a percentage, was calculated on the validation set after convergence of the training procedure. Networks were trained either with “All residues” or only with residues that showed a conservation value of 3.5 or more. The calculation of the MCC was performed over the entire original set of residues, regardless of the effect of preselection on the overall counts.
