GSVA for RNA-seq (Argonne). A. Distribution of Spearman correlation values between gene expression profiles of RNA-seq and microarray data. B. Distribution of Spearman correlation values between GSVA enrichment scores of gene sets calculated from RNA-seq and microarray data. C and D. Comparison of GSVA enrichment scores obtained from microarray and RNA-seq data for two gene sets containing genes with sex-specific expression: MSY formed by genes of the male-specific region of the Y chromosome (male-specific), and XiE formed by genes that escape X-inactivation in females (female-specific). Red and blue points represent female and male samples, respectively. In both cases GSVA scores show very high correlation between the two profiling technologies where female samples show higher enrichment scores in the female-specific gene set and male samples show higher enrichment scores in the male-specific gene set.