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Table 3 Reliability of each measurement platform in the three-modality latent variable SEM measurement model, and its correlation to the latent variable (true relative frequency of Faecalibacterium)

From: Comparative analysis of microbiome measurement platforms using latent variable structural equation modeling

 

Three- modality measurement model

Sanger

454_V3V5

qPCR

Reliability

0.911

0.822

0.452

(95% CI)

(0.775, 1.000)

(0.720, 0.912)

(0.323, 0.610)

Correlation to the latent variable

0.955

0.907

0.672

(95% CI)

(0.880, 1.000)

(0.849, 0.955)

(0.568, 0.781)

 

Sanger

454_V1V3

qPCR

Reliability

0.851

0.806

0.483

(95% CI)

(0.671, 1.000)

(0.645, 0.905)

(0.350, 0.648)

Correlation to the latent variable

0.922

0.898

0.696

(95% CI)

(0.819, 1.000)

(0.803, 0.951)

(0.592, 0.805)

  1. The 95% confidence intervals are obtained using bootstrap resampling with 100 replications. Two 3-modality models are shown with Sanger, qPCR, and 454_V3V5 in the first model, and 454_V1V3 in the second model.