Skip to main content

Table 1 Estimated Type I error rates at significant level 0.05 based on the four methods under different parameter settings of the three-component mixture distributions with τ 1 = 0.1, τ 2 = 0.9 and δ μ = 0.05

From: Age-adjusted nonparametric detection of differential DNA methylation with case-control designs

Parameter Setting π 1 π 2 π 3 μ σ t-test Linear regression Wilcox BWS
1 0.3 0.5 0.2 0.3 0.1 0.0513 0.0521 0.0514 0.0458
2 0.4 0.5 0.1 0.2 0.1 0.0495 0.0494 0.0519 0.0492
3 0.4 0.5 0.1 0.3 0.2 0.0511 0.0519 0.0503 0.0495
4 0.5 0.1 0.4 0.3 0.2 0.0528 0.0521 0.0544 0.0511
5 0.4 0.2 0.4 0.2 0.1 0.0509 0.0510 0.0472 0.0464