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Table 1 One-sample correlation network comparison of Type II diabetes versus Normal phenotype

From: An inferential framework for biological network hypothesis tests

Gene Set Name

ρ=0.35

ρ=0.50

1 KET-HG-U133A probes

0.38

0.828

2 MAP31 Inositol metabolism

0.607

0.608

3 MAP40 Pentose&glucuronate interconversions

0.599

0.574

4 MAP53 Ascorbate&aldarate metabolism

0.455

0.809

5 MAP62 Fatty acid biosynthesis path 2

0.644

0.761

6 MAP72 Synthesis&degradation of ketone bodies

0.588

0.915

7 MAP130 Ubiquinone biosynthesis

0.122

0.115

8 MAP140 C21 Steroid hormone metabolism

0.901

0.902

9 MAP271 Methionine metabolism

0.49

0.879

10 MAP272 Cysteine metabolism

0.522

0.584

11 MAP290 Valine leucine&isoleucine biosynthesis

0.139

0.431

12 MAP400 Phenylalanine tyrosine&tryptophan biosyn

0.443

0.804

13 MAP430 Taurine&hypotaurine metabolism

0.782

0.705

14 MAP450 Selenoamino acid metabolism

0.554

0.874

15 MAP460 Cyanoamino acid metabolism

0.569

0.808

16 MAP472 D-Arginine&D-ornithine metabolism

0.916

0.948

17 MAP511 N-Glycan degradation

0.58

0.677

18 MAP512 O-Glycans biosynthesis

0.613

0.673

19 MAP522 Erythromycin biosynthesis

0.081

0.254

20 MAP532 Chondroitin Heparan sulfate biosynthesis

0.726

0.882

21 MAP533 Keratan sulfate biosynthesis

0.861

0.943

22 MAP580 Phospholipid degradation

0.484

0.271

23 MAP601 Blood group glycolipid biosyn lact series

0.571

0.588

24 MAP603 Globoside metabolism

0.92

0.88

25 MAP630 Glyoxylate&dicarboxylate metabolism

0.276

0.622

26 MAP631 1-2-Dichloroethane degradation

0.473

0.797

27 MAP632 Benzoate degradation

0.515

0.812

28 MAP680 Methane metabolism

0.319

0.337

29 MAP720 Reductive carboxylate cycle CO2 fixation

0.085

0.459

30 MAP740 Riboflavin metabolism

0.231

0.583

31 MAP760 Nicotinate&nicotinamide metabolism

0.581

0.899

32 MAP780 Biotin metabolism

0.451

0.67

33 MAP900 Terpenoid biosynthesis

0.802

0.835

34 MAP950 Alkaloid biosynthesis I

0.666

0.6965

35 MAP3030 DNA polymerase

0.877

0.707

36 PYR-HG-U133A probes

0.524

0.75

37 ROS-HG-U133A probes

0.658

0.756

  1. Resample p-values for the 37 gene sets analyzed based on correlation networks using thresholds ρ = 0.35 and 0.50.