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Table 1 Scales of previously proposed models

From: Estimate hidden dynamic profiles of siRNA effect on apoptosis

 

Equations

Parameters

Fundamental model

4

12

Considering cell cycle

12

27

Considering viral effect

17

14

Self-targeting siRNA

4

8

Predator-prey model (our model)

2

4

  1. Number of equations and parameters in mathematical models which have been proposed today. Equations denotes the number of differential equations used in each model. Parameters represents the total number of parameters in each model. The fundamental model represents the basic molecular mechanisms of RNAi [3]. The models considering the cell cycle [4], considering the viral effect [5], and with self-targeting siRNA [6] target the specific phenomena, as labeled. Our model is the abstract predator-prey model and is not based on the detailed molecular mechanisms.