Unsupervised Bayesian linear unmixing of gene expression microarrays

BMC Bioinformatics

Table 7 Simulation results for real H3N2 dataset

	uBLU	PCA	NMF	BFRM	GB-GMF
Fisher criteria (× 10⁻²) (22)	6.20	2.03	6.17	4.68	2.30
RE	6.48.10 ⁻²	4.89	7.31.10⁻²	4.82	9.51.10⁻²
Time	≈ 12 h	1.5 s	116 s	≈ 47 min	≈ 10 h
Number of iterations	10 000	N/A	5 000	10 000	500

Measure of the Fisher linear discriminant measure ([23], p. 119) between post-onset symptomatic samples and the other samples on heatmaps (Figure 4), reconstruction error (RE) between the observed data and the MAP estimators, computational times (for an implementation in MATLAB 7.8.0 (R2009a) on a 3 GHz Intel(R) Core(TM)2 Duo processor), and corresponding number of iterations.

ISSN: 1471-2105