Visualization of protein interaction networks: problems and solutions

BMC Bioinformatics

Table 1 Dimensions of PINs of some organisms.

This table shows the number of known protein interactions related respectively to the Homo Sapiens, Mus Musculus, and Saccharomyces Cerevisiae organisms. For each organism, the table reports the number of proteins (#Nodes) and the number of interactions (#Edges) of the interaction network, extracted from the DIP, IntAct, MINT, I2D, and BioGrid protein interaction databases. Due to the high number of nodes and edges, it is clear that such networks need for a proper visualization tool in order to analyze effectively and quickly the enormous amount of information available. Finally, it could be noted that each database reports a different number of proteins and interactions, probably due to the curation process of such databases.

ISSN: 1471-2105