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Table 1 Performance on disulfide connectivity prediction obtained with correlated mutation measures

From: Prediction of disulfide connectivity in proteins with machine-learning methods and correlated mutations

# bonds ICOV MIp Random
  Pb = Rb Qp Pb = Rb Qp Pb = Rb Qp
2 62 62 68 68 33 33
3 52.6 42.4 47.8 37.7 20 7
4 51.8 26.8 49.4 29.3 14 1
5 39.5 16.2 33.5 13.5 11 0.1
All 51.7 43.7 49.9 44.5 23 15
  1. #bonds: number of disulfide bonds; iCOV: sparse inverse COVariance estimation; MIp: MIp: corrected Mutual Information. Random: performance obtained by a random predictor. Here Pb = Rb since the total number of predicted bonds (which is known in this experiment) is equal to the total number of observed bonds (N p = N b ). For index definition see Performance measures.