Skip to main content

Table 1 Performance on disulfide connectivity prediction obtained with correlated mutation measures

From: Prediction of disulfide connectivity in proteins with machine-learning methods and correlated mutations

# bonds

ICOV

MIp

Random

 

Pb = Rb

Qp

Pb = Rb

Qp

Pb = Rb

Qp

2

62

62

68

68

33

33

3

52.6

42.4

47.8

37.7

20

7

4

51.8

26.8

49.4

29.3

14

1

5

39.5

16.2

33.5

13.5

11

0.1

All

51.7

43.7

49.9

44.5

23

15

  1. #bonds: number of disulfide bonds; iCOV: sparse inverse COVariance estimation; MIp: MIp: corrected Mutual Information. Random: performance obtained by a random predictor. Here Pb = Rb since the total number of predicted bonds (which is known in this experiment) is equal to the total number of observed bonds (N p = N b ). For index definition see Performance measures.