Skip to main content

Table 3 Comparison among the proposed approach and some of the other approaches.

From: A knowledge-based decision support system in bioinformatics: an application to protein complex extraction

Methods

Protein complexes

Protein fraction

p-Value

G2/M transition of mitotic cell cycle

Proposed System

app1, swe1, hsl7

2/3

2.17e-03

PINCoC

swe1, hsl7

2/2

6.90e-04

UVCluster

app1, swe1, hsl7

2/3

2.17e-03

Actin Filament Depolymerization

Proposed System

act1, srv2, bnr1, bni1, cof1, trm5, aip1

4/7

4.92e-10

PINCoC

bnr1, bni1, pfy1, act1, srv2, aip1, trm5

5/7

1.52e-07

UVCluster

act1, srv2, aip1, trm5, cof1

4/5

7.30e-04

Actin Cytoskeleton Organization

Proposed System

sla2, abp1, yor284w, rvs167, ysc84, sla1, ynl086w, ypl246c, rvs161, acf2, ybr108w, yjr083c, ygr268c, ypr171w, yhr133c

7/15

4.65e-08

PINCoC

sla2, abp1, yor284w, rvs167, ysc84, app1, rvs161, ynl086w, yjr083c, acf2

6/10

6.72e-08

UVCluster

sla2, abp1, yor284w, rvs167, ysc84, sla1, ygr268c

4/7

5.93e-05

Actin Polymerization or Depolymerization

Proposed System

crn1, svl3

0/2

> 0.01

PINCoC

crn1, svl3, las17, yhr133c, cof1

3/5

9.07e-06

UVCluster

crn1, svl3

0/2

> 0.01

Rho Protein Signal Trasduction

Proposed System

----

---

---

PINCoC

cdc42, cla4, gic2

3/3

1.76e-06

UVCluster

cdc42, cla4, gic2

3/3

1.76e-06

  1. The table reports a comparison among the proposed approach and two different approaches, called respectively PINCoC and UVCluster, that have been previously tested with this database. Proposed system outperforms result of the other tools with respect to the complexes Actin Filament Depolymerization and Actin Cytoskeleton Organization.