VarBin, a novel method for classifying true and false positive variants in NGS data

BMC Bioinformatics

Table 1 Sanger sequencing result is compared with the VarBin variant classification Bin

Bin	Sanger result	Total*	SNV	Indel
Bin 1	true	33	23	10
	false	1	1	-
Bin 2	true	10	8	2
	false	23	21	2
Bin 3	true	-	-	-
	false	16	16	-
Bin 4	true	-	-	-
	false	11	11	-

*98 variants were sequenced in the proband, the proband's family, or other families in the background data sets as stated in the methods. Four of the 98 could not be Sanger sequenced and were excluded from this table (94 total variants shown). SNV, single nucleotide variant; Indel, and insertion or deletion.

ISSN: 1471-2105