The occurrence of Met versus other hydrophobic amino acids vicinal to phosphorylation sites. (A) The heat map indicates the proportion of phosphorylation sites at each level of Met conservation. Many phosphorylation sites with conserved (e.g., ≥ 6/8) Met are present across different (eight) taxa. (B) Proportion (%) of sequences (in disparate taxa) including a hydrophobic (Val/Ile/Leu/Phe) residue. At higher Met conservation, a higher proportion (%) of remaining sequences includes a hydrophobic residue in place of Met.