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Figure 6 | BMC Bioinformatics

Figure 6

From: Circles within circles: crosstalk between protein Ser/Thr/Tyr-phosphorylation and Met oxidation

Figure 6

Results from GO term enrichment analyses. The A. thaliana proteins (test set) that contain a known phosphorylation site (based upon published data from A. thaliana, G. max, or O. sativa) including a Met residue within the ± 6 residue window shows significant enrichment (p < 0.005, hypergeometric test, X-axis shows the log2 ratio of number of each significantly enriched GO term in test set against background set) for several GO terms when the Met is conserved (panel A ≥7, B ≥6, C ≥5 and D ≥4) in eight disparate taxa. As the Met conservation level decreases the significance of the GO term enrichment decreases compared to the background of A. thaliana P-proteins. The GO term enrichment results agree with the proposal that Met oxidation:phosphorylation-site cross-talk is most likely in kinases (green bars) and various stress-related proteins (red bars).

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