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Table 2 miRanda and TargetScan score parameters can predict co-expression

From: mirCoX: a database of miRNA-mRNA expression correlations derived from RNA-seq meta-analysis

Data Source Parameter Pearson Correlation -log10 (P-Value)
miRanda conserved Alignment Score 0.041 69.83
  Conservation Score -0.023 22.16
  Free Energy 0.024 23.33
  mirSVR Score -0.02 16.6
miRanda nonconserved Alignment Score 0.026 139.55
  Conservation Score -0.025 130.38
  Free Energy -0.08 > 307
  mirSVR Score 0.024 120.49
TargetScan Aggregate PCT 0.023 5.51
  Context Score -0.112 141.13
  # Conserved Sites 0.0299 9.61
  # Nonconserved Sites -0.064 45.92
  # Conserved 7mer-1a sites 0.019 3.27
  # Conserved 7mer-m8 sites 0.014 1.39
  # Conserved 8mer sites 0.02 4.2
  # Nonconserved 7mer-1a sites -0.094 99.64
  # Nonconserved 7mer-m8 sites 0.031 10.64
  # Nonconserved 8mer sites -0.008 0
  1. For each predicted miRNA-mRNA pair from the miRanda conserved, miRanda nonconserved, and TargetScan datasets, the Pearson correlation coefficient for co-expression across multiple RNA-seq experiments was obtained. The correlation coefficient was then compared to various predictor variables provided by miRanda/TargetScan, across all pairs, again using Pearson correlation. (P-values after Bonferroni correction; * indicates significance at p < 0.05; ** indicates significance at p < 0.001).