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Table 1 Performance of 'RNAfold' derived sequence-based SVM models for Dicer cleavage sites at 5p and 3p arm.

From: PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors

Features Window size CD-5p (sequence-based) CD-3p (sequence-based)
   Sn Sp Ac Mc Sn Sp Ac Mc
Mono 8 58.20 61.80 60.00 0.20 58.38 59.28 58.83 0.18
  10 63.78 58.92 61.35 0.23 60.36 61.44 60.90 0.22
  12 61.08 63.96 62.52 0.25 64.68 59.46 62.07 0.24
  14 60.36 64.86 62.61 0.25 63.78 66.49 65.14 0.30
Dinuc 8 59.82 59.82 59.82 0.20 61.80 52.25 57.03 0.14
  10 60.54 58.20 59.37 0.19 58.74 52.97 55.86 0.12
  12 61.44 56.40 58.92 0.18 60.90 61.62 61.26 0.23
  14 60.72 65.05 62.88 0.26 60.36 65.95 63.15 0.26
Trinuc 8 60.90 57.48 59.19 0.18 58.92 56.04 57.48 0.15
  10 55.14 61.62 58.38 0.17 59.82 53.15 56.49 0.13
  12 58.92 55.14 57.03 0.14 63.24 57.12 60.18 0.20
  14 60.72 58.74 59.73 0.19 64.68 60.90 62.79 0.26
Binary 8 60.54 61.62 61.08 0.22 65.23 65.05 65.14 0.30
  10 61.26 63.78 62.52 0.25 67.75 63.06 65.41 0.31
  12 67.57 65.05 66.31 0.33 69.55 66.13 67.84 0.36
  14 71.89 77.12 74.50 0.49 70.99 63.96 67.48 0.35
  1. Models were developed using composition and binary pattern of different window sizes. Patterns were taken from sequence of Dicer cleavage site of 5p arm (sequence of CP-5p) and 3p arm (sequence of CP-3p) using miRNA.str data.
  2. CD-5p: Dicer cleavage site at 5p arm, CD-3p: Dicer cleavage site at 3p arm, Mono: Mononucleotide, Dinuc: Dinucleotide, Trinuc: Trinucleotide, Binary: Binary pattern, Sn: sensitivity, Sp: specificity, Ac: accuracy, Mc: Matthews correlation coefficient.