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Table 3 Performance of 'quikfold' derived sequence- and structure-based SVM models for Dicer cleavage sites at 5p arm.

From: PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors

Features Window size CD-5p (sequence-based) CD-5p (structure-based)
   Sn Sp Ac Mc Sn Sp Ac Mc
Mono 8 56.76 56.94 56.85 0.14 69.37 70.45 69.91 0.40
  10 59.10 56.40 57.75 0.16 75.68 77.48 76.58 0.53
  12 54.05 57.84 55.95 0.12 77.84 83.06 80.45 0.61
  14 58.20 59.64 58.92 0.18 81.44 82.70 82.07 0.64
Dinuc 8 58.92 59.46 59.19 0.18 65.95 67.03 66.49 0.33
  10 55.50 61.08 58.29 0.17 67.39 67.57 67.48 0.35
  12 59.82 56.76 58.29 0.17 69.73 74.41 72.07 0.44
  14 64.14 54.95 59.55 0.19 73.33 73.33 73.33 0.47
Trinuc 8 61.98 52.43 57.21 0.14 60.36 59.10 59.73 0.19
  10 55.32 50.45 52.88 0.06 66.31 62.34 64.32 0.29
  12 57.48 56.58 57.03 0.14 65.77 65.41 65.59 0.31
  14 61.26 60.18 60.72 0.21 68.65 65.41 67.03 0.34
Binary 8 62.70 58.92 60.81 0.22 69.55 78.02 73.78 0.48
  10 61.26 59.46 60.36 0.21 76.40 80.36 78.38 0.57
  12 65.41 63.42 64.41 0.29 82.16 81.26 81.71 0.63
  14 62.52 69.73 66.13 0.32 85.23 87.21 86.22 0.72
  1. Models were developed using composition and binary pattern of different window sizes. Patterns were taken from sequence of Dicer cleavage site of 5p arm (sequence of CP-5p) and structure of Dicer cleavage site of 5p arm (structure of CP-5p).