From: In silico experimental evolution: a tool to test evolutionary scenarios
Parameter | Symbol | Value |
---|---|---|
Population size | N | 1,000 |
Size of the initial (random) genome | L init | 5,000 base pairs |
Promoter sequence | 0101011001110010010110, with up to dmax = 4 mismatches | |
Terminator sequences |
| |
Initiation signal for the translation | 011011****000 | |
Termination signal for the translation | 001 | |
Genetic code | See Figure 1 | |
Global set of "cellular processes" | Ω | [0,1] |
Maximal pleiotropy of the proteins | w max | 5.10-3 |
Environmental target fluctuates around... |
| See Figure 1 |
Environmental fluctuations: characteristic time | τ | 2,500 |
Environmental fluctuations: standard deviation | σ | 5.10-3 |
Selection intensity | k | 750 initially, then 250 |
Point mutation rate | u point | 5.10-6 per bp |
Small insertion rate | u smallins | 5.10-6 per bp |
Small deletion rate | u smalldel | 5.10-6 per bp |
Large deletion rate | u largedel | 5.10-5 per bp |
Duplication rate | u duplic | 5.10-5 per bp |
Inversion rate | u inv | 5.10-5 per bp |
Translocation rate | u transloc | 5.10-5 per bp |
Length of small indels | Uniform law bw. 1 and 6 bp |