Skip to main content
Figure 1 | BMC Bioinformatics

Figure 1

From: Mapping proteins in the presence of paralogs using units of coevolution

Figure 1

Two alignments of protein families A and B with proteins from two species, which are indicated by different background colors. Black and red nodes and edges compose the matching graph G. A matching θ is shown in red. A unit of coevolution ((a, b), (a', b')) within θ is highlighted in bold. For this toy example, we have A (a, a') = 12 (matches + mismatches), ∆ A (a, a') = 11 (mismatches), B (b, b') = 19 and ∆ B (b, b') = 15 and a resulting probability f ( Δ A ( a , a ) , Δ B ( b , b ) ) = 12 11 19 15 / 31 26 0 . 274 . Note the lower score of the unit ((a', b'), (a", b")), which is 12 11 19 3 31 14 4 . 4 1 0 - 5 .

Back to article page