Figure 8

Comparison of the RMSD of the wild type and E104D mutant structures in molecular dynamics simulations. The RMSD of (A) the whole protein, (B) regions A, B and C in the subunit interfaces and (C) interfacial region A. RMSD (Å) values for each frame are calculated with the initial structures as the references. In all subfigures, the RMSD of the wild type structure is shown as black solid lines while the RMSD of the mutant structure is shown as red dashed lines.