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Table 2 Comparison between HsTIM wild type and E104D mutant dimer interfaces.

From: Structural analysis on mutation residues and interfacial water molecules for human TIM disease understanding

Properties

∆SASA (Å2)

#Water

#Atoms

wetness

rWBL

Wild type

1800.6

25

546

0.046

1.28

E104D

1761.8

25

545

0.046

1.18

  1. Overall comparison of the ∆SASA, #Water (number of interfacial water molecules), #Atoms (number of interfacial atoms), wetness and rWBL between HsTIM wild type and E104D mutant dimer interfaces.