Table 7 Additional conserved complexes found in yeast
From: Identifying conserved protein complexes between species by constructing interolog networks
ID | Complex name | Size | Jaccard score | Functional category | Functional description |
|---|---|---|---|---|---|
96 | eIF3 complex | 7 | 0.63 | Translation | Eukaryotic translation initiation factor |
247 | Transcription factor TFIID complex | 15 | 0.73 | Transcription | mRNA synthesis |
27 | DNA-directed RNA polymerase II complex | 12 | 0.69 | Transcription | mRNA synthesis |
45 | DNA replication factor C complex (Rad24p) | 5 | 0.67 | DNA processing | DNA synthesis and replication |
152 | DNA replication factor C complex (Rcf1p) | 5 | 0.67 | DNA processing | DNA synthesis and replication |
294 | Mcm2-7 complex | 6 | 0.6 | DNA processing | Chromosome maintainance, DNA synthesis and replication |
268 | SF3b complex | 6 | 0.57 | RNA processing | mRNA splicing |
65 | U6 snRNP complex | 8 | 0.5 | RNA processing | This complex combines with other snRNPs, unmodified pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs. |
375 | AP-3 adaptor complex | 4 | 0.67 | Cellular transport, vesicular transport | This complex is responsible for protein trafficking to lysosomes and other related organelles. |
25 | 20S proteasome | 14 | 0.5 | Cell cycle, protein fate | Proteasomal degradation (ubiquitin/proteasomal pathway), protein processing (proteolytic) |
137 | Chaperonin-containing T-complex | 8 | 0.67 | Protein fate | A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor. |