Skip to main content

Table 7 Additional conserved complexes found in yeast

From: Identifying conserved protein complexes between species by constructing interolog networks

ID Complex name Size Jaccard score Functional category Functional description
96 eIF3 complex 7 0.63 Translation Eukaryotic translation initiation factor
247 Transcription factor TFIID complex 15 0.73 Transcription mRNA synthesis
27 DNA-directed RNA polymerase II complex 12 0.69 Transcription mRNA synthesis
45 DNA replication factor C complex (Rad24p) 5 0.67 DNA processing DNA synthesis and replication
152 DNA replication factor C complex (Rcf1p) 5 0.67 DNA processing DNA synthesis and replication
294 Mcm2-7 complex 6 0.6 DNA processing Chromosome maintainance, DNA synthesis and replication
268 SF3b complex 6 0.57 RNA processing mRNA splicing
65 U6 snRNP complex 8 0.5 RNA processing This complex combines with other snRNPs, unmodified pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs.
375 AP-3 adaptor complex 4 0.67 Cellular transport, vesicular transport This complex is responsible for protein trafficking to lysosomes and other related organelles.
25 20S proteasome 14 0.5 Cell cycle, protein fate Proteasomal degradation (ubiquitin/proteasomal pathway), protein processing (proteolytic)
137 Chaperonin-containing T-complex 8 0.67 Protein fate A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.