Table 1 Principal model parameters
From: Agent based modeling of Treg-Teff cross regulation in relapsing-remitting multiple sclerosis
Parameter | Value (estimate) | Meaning |
|---|---|---|
treg_radius | 3 | max visibility radius of Treg |
eff_dup | 0.1 (range 0.025 - 0.2) Δ(t)- 1[13] | max. duplication rate of Teff |
init_mye | 100 | initial quantity of myelin per patch |
eat_mye | 5 | quantity of myelin destroyed by Teff |
p t | 0.1 in healthy patients 0.025 in hill patients (range 0.025 - 0.2) Δ(t)- 1[13] | max. duplication rate of Treg |
patch_density | 3 | max. no of entities per patch allowed to have duplication |
Teff_life | 60 (range 50-70) [58] Δ(t) | Teff mean half-life |
Treg_life | 60 (range 50-70) [58] Δ(t) | Treg mean half-life |