Skip to main content
Figure 9 | BMC Bioinformatics

Figure 9

From: Towards accurate modeling of noncovalent interactions for protein rigidity analysis

Figure 9

Baseline comparison of B-cubed scores of RigidFinder data set. Mean of differences and p-values for each decomposition method (listed in Table 3), compared with all-rigid baseline (method 2) and KINARI v1.0 (method 3). Results include only the RigidFinder portion of the data set (see Figure 8). The mean of differences measures the change in B-cubed score between the two methods; a better-performing method will have a higher associated mean of differences. The p-value indicates whether the improvement is significant (p-value≤ 0.05 is deemed significant). The greatest improvement in B-cubed scores, most significantly in the small to medium sized proteins, resulted when both the modeling of hydrogen bonds and hydrophobic interactions were varied (method 7).

Back to article page