Table 4 Effect of flanking peptides on the binding affinity to HLA DRB1*1501 allele.
From: Prediction of peptides binding to MHC class I and II alleles by temporal motif mining
Experimental | ARB | NetMHCIIpan | SMM_align | NN_align | MHC-PPM | |
|---|---|---|---|---|---|---|
Sequence | IC50(nM) | IC50(nM) | IC50(nM) | IC50(nM) | IC50(nM) | IC50(nM) |
ENPVVHFFKNIVTPR | 33 | 21.9 | 10 | 21 | 8 | 11 |
VVHFFKNIVHAAA | 33 | 21.9 | 9.2 | 52 | 10.7 | 139 |
VVHFFKNIVTAAA | 45 | 21.9 | 9.5 | 20 | 11.5 | 224 |
VVHFFKNIVTK AA | 35 | 21.9 | 8.1 | 20 | 10.5 | 142 |
VVHFFKNIVTAK A | 4 | 21.9 | 8.1 | 20 | 9.8 | 83 |
VVHFFKNIVTAAK | 5 | 21.9 | 8.9 | 20 | 11.1 | 263 |
D AVVHFFKNITVA | 326 | 82.5 | 23.6 | 25 | 23.8 | 316 |
AD VVHFFKNITVA | 454 | 82.5 | 23.8 | 25 | 23.9 | 320 |
AAD VHFFKNITVA | 264 | 1286.7 | 45 | 30 | 74.4 | 392 |
RMSE | 371.90 | 190.78 | 191.84 | 187.13 | 134.35 | |
Pearson's Corr. | 0.349 | 0.728 | 0.041 | 0.540 | 0.721 |