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Table 2 Top 20 term associations in category "overlap but not identical" that were identified by CroGO.

From: Identifying cross-category relations in gene ontology and constructing genome-specific term association networks

MF Name BP Name Evidence
polynucleotide adenylyltransferase activity ncRNA polyadenylation NEW
TFIIF-class binding TF activity regulation of transcription-coupled nucleotide-excision repair REF [37]
TFIIF-class binding TF activity positive regulation of transcription elongation from Pol I promoter REF [38]
TFIIF-class binding TF activity regulation of transcription elongation from Pol I promoter REF [38]
TFIIF-class binding TF activity positive regulation of histone H3-K36 trimethylation NEW
TFIIF-class binding TF activity regulation of histone H3-K36 trimethylation NEW
TFIIF-class binding TF activity positive regulation of histone H3-K36 methylation NEW
TFIIF-class binding TF activity regulation of nucleotide-excision repair REF [39]
TFIIF-class binding TF activity regulation of histone H2B ubiquitination REF [40]
TFIIF-class binding TF activity positive regulation of phosphorylation of Pol II C-terminal domain serine 2 residues NEW
TFIIF-class binding TF activity regulation of phosphorylation of Pol II C-terminal domain serine 2 residues NEW
TFIIF-class binding TF activity regulation of histone H2B conserved C-terminal lysine ubiquitination NEW
IMP dehydrogenase activity GTP biosynthetic process REF [41]
hydrogen ion transporting ATP synthase activity, rotational mechanism ATP biosynthetic process LEXICAL
RNA-directed RNA polymerase activity tRNA transcription from Pol III promoter LEXICAL
RNA-directed RNA polymerase activity tRNA transcription NEW
protein prenyltransferase activity protein geranylgeranylation REF [42]
second spliceosomal transesterification activity generation of catalytic spliceosome for second transesterification step NEW
oxoglutarate dehydrogenase activity 2-oxoglutarate metabolic process LEXICAL
peptide alpha-N-acetyltransferase activity N-terminal protein amino acid acetylation REF [43]
  1. Top 20 term associations in category "overlap but not identical" that were identified by CroGO. In the list, 8 term associations are supported by the existing biological studies, 3 are supported by the lexical matching on term definition, and the rest 7 are new conceptual connections that cannot be found in any literature. Only 3 of the term associations can be identified by the VSM or ASR based measures.