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Table 1 Results for knockout strains derived by OptKnock on the core E. coli metabolic network

From: Adaptive bi-level programming for optimal gene knockouts for targeted overproduction under phenotypic constraints

   OptKnock MOMA Flux  
K Knockouts Succi Biomass Succi Biomass v - w L 2
2 kdpg→ pyr + gap (or 6pg→kdpg), fadh2 + 0.5o2→2atp (or suc→ fum + fadh2) 102.98 14.36 26.32 13.18 398.75
3 g6p → 6pg + nadph, 3pg+glu→ser+akg+nadh, nadh → nadph 121.02 7.06 24.45 5.23 633.25
4 g6p → 6pg + nadph, dhap → gap, fadh2 + 0.5o2→2atp (or suc→fum + fadh2), glyc → glyc(ext) 118.71 5.00 84.56 5.00 482.70
5 pep → pyr + atp, mal→ pyr+co2 + nadph, dhap + nadh → glyc3p, glyc3p → glyc, fadh2 + 0.5o2→2atp (or suc→fum + fadh2) 126.33 10.91 38.73 12.75 518.65