Table 1 Results for knockout strains derived by OptKnock on the core E. coli metabolic network
OptKnock | MOMA Flux | |||||
|---|---|---|---|---|---|---|
K | Knockouts | Succi | Biomass | Succi | Biomass |
|
2 | kdpg→ pyr + gap (or 6pg→kdpg), fadh2 + 0.5o2→2atp (or suc→ fum + fadh2) | 102.98 | 14.36 | 26.32 | 13.18 | 398.75 |
3 | g6p → 6pg + nadph, 3pg+glu→ser+akg+nadh, nadh → nadph | 121.02 | 7.06 | 24.45 | 5.23 | 633.25 |
4 | g6p → 6pg + nadph, dhap → gap, fadh2 + 0.5o2→2atp (or suc→fum + fadh2), glyc → glyc(ext) | 118.71 | 5.00 | 84.56 | 5.00 | 482.70 |
5 | pep → pyr + atp, mal→ pyr+co2 + nadph, dhap + nadh → glyc3p, glyc3p → glyc, fadh2 + 0.5o2→2atp (or suc→fum + fadh2) | 126.33 | 10.91 | 38.73 | 12.75 | 518.65 |