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Table 2 Results for knockout strains derived by MOMAKnock on the core E. coli metabolic network

From: Adaptive bi-level programming for optimal gene knockouts for targeted overproduction under phenotypic constraints

   MOMAKnock MOMA Flux  
K Knockouts Succi Biomass Succi Biomass v - w L 2
2 6pg→ ru5p+co2+nadph, suc→ fum + fadh2 (or fadh2 + 0.5o2→2atp) 54.41 13.44 40.25 12.65 124.86
3 6pg→ru5p+co2+nadph, fadh2+0.5o2 → 2atp (or suc→ fum + fadh2), ser→ gly + meethf 54.98 12.08 45.71 11.80 157.67
4 pep→ pyr + atp, g6p→ 6pg+nadph, 6pg→ kdpg (or kdpg→ pyr + gap), fadh2 + 0.5o2→2atp (or suc→ fum + fadh2) 57.75 11.24 52.73 10.76 318.52
5 pep → pyr + atp, g6p → 6pg + nadph, 6pg→ kdpg (or kdpg→ pyr + gap), fadh2+0.5o2→2atp (or suc→ fum + fadh2), nadh → nadph 65.25 7.90 53.31 7.65 352.26