Table 2 Results for knockout strains derived by MOMAKnock on the core E. coli metabolic network
MOMAKnock | MOMA Flux | |||||
|---|---|---|---|---|---|---|
K | Knockouts | Succi | Biomass | Succi | Biomass |
|
2 | 6pg→ ru5p+co2+nadph, suc→ fum + fadh2 (or fadh2 + 0.5o2→2atp) | 54.41 | 13.44 | 40.25 | 12.65 | 124.86 |
3 | 6pg→ru5p+co2+nadph, fadh2+0.5o2 → 2atp (or suc→ fum + fadh2), ser→ gly + meethf | 54.98 | 12.08 | 45.71 | 11.80 | 157.67 |
4 | pep→ pyr + atp, g6p→ 6pg+nadph, 6pg→ kdpg (or kdpg→ pyr + gap), fadh2 + 0.5o2→2atp (or suc→ fum + fadh2) | 57.75 | 11.24 | 52.73 | 10.76 | 318.52 |
5 | pep → pyr + atp, g6p → 6pg + nadph, 6pg→ kdpg (or kdpg→ pyr + gap), fadh2+0.5o2→2atp (or suc→ fum + fadh2), nadh → nadph | 65.25 | 7.90 | 53.31 | 7.65 | 352.26 |