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Table 3 Results for knockout strains derived by MOMAKnock on the iAF1260 E. coli metabolic network

From: Adaptive bi-level programming for optimal gene knockouts for targeted overproduction under phenotypic constraints

   MOMAKnock MOMA Flux  
K Knockouts Succi Biomass Succi Biomass v - w L 2
3 q8+succ→fum+q8h2, 6pgl+h2o→6pgc+h, (2)h2o + o2 + urate → alltn + co2 + h2o2 39.30 5.02 27.45 5.02 906.49
4 q8+succ→fum+q8h2, ac + atp → actp + adp, h2o+methf→10fthf+h, r5p+xu5p-D→g3p+s7p 67.08 5.02 63.23 5.02 402.33
5 q8+succ→fum+q8h2, glu-L+h→4abut+co2, 3pg+nad→3php+h+nadh, 3php+glu-L→akg+pser-L, 6pgc+nadp→co2+nadph+ ru5p-D 74.94 5.02 66.67 5.02 464.76